Binding of the Spire

Play Isaac in Slay the Spire 2, with Isaac monsters, bosses, items, cards and events drawn from your own installed copy of The Binding of Isaac: Rebirth.

Relics reshape your Tears with multishot, piercing, poison, slow, charm, fear, lasers and rocket splash. Carry one active-item card, starting with D6, or find Backpack to carry two. New events offer active items and let you replace your current one.

Version 0.5.0 expands the roster to 42 encounters with Act 2/3 monsters, Deadly Sin elites, Isaac creature animations and rotating bosses. It also includes 22 added relics, nine added cards, three active-item events and fixes for shops, boss encounters, event rewards and the ending. Tarots are free, powerful consumables that permanently leave your deck when used. Nickel is a rare coin card with its Isaac artwork, and Mom, Monstro and Duke of Flies are larger in battle.

Requires Slay the Spire 2 and The Binding of Isaac: Rebirth on Windows. Tested against Slay the Spire 2 version 0.107.1. BaseLib is included. Isaac graphics and sounds are read from the player's own copy; original game content is not distributed.

Tested for solo play. Co-op compatibility has not been verified. Earlier card/relic changes passed assembly checks; the current expanded build still needs a complete gameplay pass.

Credits: original IsaacSpire manifest credits rami; subsequent changes made with Codex. BaseLib by Alchyr and contributors, distributed under its MIT license: https://github.com/Alchyr/BaseLib-StS2. Slay the Spire 2 and The Binding of Isaac belong to their respective creators.